Tuesday, February 3, 2015

Role of Clinical Pharmacist in Disease and Drug Therapy Management at a Tertiary Care Hospital - Few Case Studies


Objective: To highlight the role and responsibilities of a Clinical Pharmacist in disease and drug therapy management at a tertiary care hospital.

Background: With recent advancements in drug therapy management and increasing volume of new information continuously pouring in areas of pharmaceutical formulations, pharmacokinetics, dosing, pharmacodynamics, adverse effects, drug interactions, patient compliance, pharmacogenomics and pharmacoeconomics, new challenges are being posed to the healthcare personnel for optimizing clinical outcomes of pharmacotherapeutics among patients. With this very objective this paper presents observations, interventions and outcomes of a clinical pharmacist led initiatives in a few wards of a tertiary care hospital during the course of his routine practical training work and highlights the benefits that such services can yield to the patients by way of assistance offered to the other partners of healthcare system.

Methodology: The study was carried out in four different wards of a tertiary care hospital over a period of four months. A total of 12 cases were selected out of which 3 were from Cardiology, 3 from General Medicine 2 from Gastroenterology and 4 from Accident and Emergency wards. Data was collected from patient record files by examining the patients' demographic data, past medical and medication history, laboratory investigations. Data was also collected from treatment charts and individual patient interviews. During the entire period of study, selected cases in the respective wards were continuously monitored for patients’ drug related needs and problems and all cases were followed up till their discharge from the hospital.

Results: Present study revealed that total no. of drugs prescribed  to these 12 patients under study were 85 and average no. of drugs prescribed per patient was 7 out of which most frequently prescribed therapeutic class of drugs was antibiotics (16), followed by Proton Pump Inhibitors (12), vitamins and supplements(12), antihypertensive (08), anticoagulants (5), steroids (4) and others (28). No. of injectables prescribed were 42 out of a total of 85 drugs. Other parameters like total no. of drug related problems, patients related needs, no. of patients counselled, no. of drug interactions identified are discussed in detail.

Conclusion:  Hospitalized patients in medicine-related wards have a wide range of diseases and are frequently prescribed with large number of drugs which makes drug therapy complex. Therefore Clinical Pharmacy services can help in monitoring of drug therapy and addressing the patients’ actual drug related needs and problems. This paper underlines the need to include a clinical pharmacist in daily ward rounds and seek his assistance is making the best possible pharmacotherapeutic options available to the patients and thereby minimize unwanted effects and improve his health related quality of life.
 
Key Words: Drug therapy management; Disease management; Clinical Pharmacy Services; Tertiary care hospitals; Drug related problems; Drug related needs

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