Sunday, February 5, 2017

JKMSCL and the quality of drugs supplied to govt. hospitals

Dr Geer Mohammad Ishaq in his article published by Daily Greater Kashmir for publication dwells upon the measures needed to be taken by JKMSCL in order to ensure quality and streamline supply of medicines in the state

J&K Medical Supplies Corporation Limited has once again been in news albeit for wrong reasons. Several cases of substandard drugs being supplied by JKMSCL to government hospitals have surfaced in recent past that includes a spine-chilling case of steroids and antibiotics being supplied together in the same boxes in large quantities for use by children at a pediatric hospital. Boxes of antibiotic Vancomycin injection were found to contain vials of Prednisolone injection, a steroid and both the injections had same size, labeling and packaging design and even the same batch number, making it difficult to differentiate between the two without going through the labeling information. As many as 7000 vials were confiscated by the drug control officials from the hospital apart from seizing additional 12000 vials from the drug warehouse at Government Medical College, Srinagar. Any use of steroid in place of an antibiotic would have wreaked disaster among pediatric patients making them vulnerable to potentially serious health hazards. Recently it also came to the fore that five out of the six substandard drugs supplied by the JKMSCL to the state hospitals during past few months had come from a single Himachal Pradesh based company against which reportedly no immediate action was taken due to some “procedural formalities”. 

The minister for Health and Medical Education of the state is on record to have admitted on the floor of the House that 85 drugs were found to be sub-standard including drugs like Amoxicillin capsules and Ceftriaxone injections supplied by Jammu and Kashmir Medical Supplies Corporation Limited. Earlier a CAG report tabled in the state legislative assembly had also brought to light some serious lapses in the procurement processes for equipments and supplies in J&K Health Department, and had also depicted gross negligence and apathy on part of the officials in ensuring supply of quality and safe medicines to patients that can be gauged from the fact that as per this report, 50.95 lakh sub-standard tablets, capsules and injections had been issued to patients in various govt. hospitals. CAG report has also revealed acute deficiency of drugs and disposables for testing in healthcare institutes. All this has led to soaring mass resentment and anxiety and has further diminished already plummeted faith and trust of common people upon medicines being issued at public health facilities.

Local print media particularly GK has been doing a commendable job in highlighting these crucial issues of high importance having serious implications on overall public health. However, while rightly blaming the faulty drug procurement and flawed quality testing procedures being adopted by JKMSCL at present, for the dismal scenario, some sections of the pharmaceutical traders as well as medical fraternity have also been suggesting winding up of the whole JKMSCL and reverting back to previous mode of decentralized procurement by different institutions and departments in a fragmented manner. Question is whether dissolution and dismantling of JKMSCL is the right answer to the miseries of common masses vis-à-vis quality and availability of medicines at govt. health centres. Answer inevitably is a clear ‘No’ since JKMSCL is a step in the right direction taken on the basis of premier drug policy of the J&K state that was formulated and adopted by the state govt. in the year 2012.

Main purpose behind establishing JKMSCL was to centralize procurement and decentralize distribution of standard quality medicines on the lines of Tamil Nadu and Rajasthan Medical Services Corporations which have been successful, WHO-endorsed models in this field and have led to conservation of 38 to 45% of financial resources meant for drug procurement that in turn has directly benefited patients of these states for whom availability and affordability of standard quality generic medicines has drastically improved. Since getting good health care is not a privilege but a fundamental right of every human being, a just and humane society must be able to provide reasonable, universal access to safe, effective and standard quality medicines to all its citizens irrespective of their caste, creed, religion or their paying capacity. Universal access to health care is well recognized as a basic right of the people under the right to protection of life and personal liberty as enshrined under Article 21 of the Constitution of India as well as under Section 24 of the Constitution of Jammu & Kashmir state. Therefore main idea behind JKMSCL was to pool all the previously fragmented and dispersed financial resources meant for procurement of quality medicines and to utilize them to the best possible benefits of patients. Hence those who talk of its dismantling or dissolution cannot be considered as the well-wishers of patients. Then the next obvious question would be as to where does the actual fault lie and what needs to be done to rectify the same.

Roots of the problem lie in the fact that JKMSCL is functioning in the state in absence of proper drug procurement policy framework, there is lack of adequate, scientific warehousing and inventory management system that includes state-of-the-art drug storage facilities fully equipped with Management Information System (MIS) for real-time monitoring of stocks in all districts and divisions of the state, lack of sufficient, dedicated transportation vehicles laced with cold-chain facilities, non-availability of qualified and adequate manpower trained specifically in supply chain management, paucity of funds for procurement as well as non-procurement purposes, lack of adequate, sophisticated drug testing facilities and deficiency of frequent, random drug sampling procedures, non-compliance with stringent pre- and post-qualification criteria to promote competition and enforce quality, dearth of scientific demand estimation and forecasting system to accurately quantify procurement, well defined, precise and localized Essential Drugs List, protocols for regular inspection of supplier premises and mandatory multiple external quality testing. A lot can be written about each of these supply chain management activities, however due to constraints of space only a couple of important issues shall be briefly discussed in the remaining part of this write-up.

While the spirit with which JKMSCL was established is admirable, the way it is functioning is unscientific and needs some serious thinking. No such corporation can be a success unless it is fully autonomous, completely transparent and accountable and functions on well established scientific principles of pharmaceutical supply chain management. There is need to streamline the entire system on modern, scientific and professional lines and organize all its activities in a systematic manner in tune with international standards and norms. A foolproof quality assurance system needs to be adopted leaving no room at all for any compromises on the quality of medicines being supplied to patients. Government needs to engage suitably qualified and adequately trained personnel for the purpose of drug procurement, demand estimation, quantification, pre-qualification and post-qualification procedures. At present no such executive or administrative staff is available in sufficient numbers exclusively for medicine management activities at any of the government health departments of J&K state like Departments of Health, Family Welfare, Medical Education, Provincial Medical Stores or Govt. Medical College, Srinagar that are adequately trained to serve the purpose. Furthermore JKMSCL needs to fulfill all necessary pre-requisites like state-of-art warehouses, dedicated transportation, qualified manpower, adequate funds, sophisticated quality testing facilities, regular inspections of retail outlets and frequent drug sampling in order to bring it back on track and fulfill its objectives. In absence of such a robust mechanism JKMSCL will continue to fail in its objectives of making standard quality medicines available throughout the year without any stock-outs in all healthcare facilities of the state.

Establishment of a comprehensive Quality Assurance system involving both surveillance and testing of drug quality, involving both technical and managerial activities, helps in ensuring quality of the medicines. Various national standards suggest that drug quality should be assessed as compliance with pharmacopoeial specifications concerning a drug’s identity, purity, potency and other characteristics like uniformity of the dosage form, bioavailability, bioequivalence and stability. Basic quality assurance procedures like visual inspection of labelling carried out by a qualified pharmacist can easily be adopted at facility level. Random sampling of drug consignments for the purpose of testing soon after its procurement as well as from district and block level health facilities after distribution is an important step in ensuring quality of medicines. However JKMSC must not rely completely upon the insufficient govt. drug testing facilities available in the state. It must empanel accredited private drug testing laboratories on the lines of Tamil Nadu Medical Services Corporation and send coded samples to them for testing after carrying out due process of their validation. Meanwhile govt. needs to accord top priority to augmenting drug testing facilities in the state on modern lines by installing state-of-the-art sophisticated equipments and mobile testing vans laced with all the modern gadgetry required to test drugs on the spot in far flung areas. Gujarat FDA has taken lead in this respect by procuring around 30 mobile testing vans that are able to reach any nook and corner of the state and conduct on-the-spot testing of drugs without even opening the containers at the first instance. Our state too needs to follow the suit.

Inappropriate and inefficient medicine procurement system leads to sub-optimal use of resources with poor value for money. Government needs to promulgate a robust drug procurement policy and implement the drug policy in letter and spirit that has already been approved by the state assembly five years back. It is highly deplorable on part of the government that even after the lapse of five years drug policy is still awaiting implementation because of which poor patients are suffering for want of good quality medicines at government health facilities of the state. In this direction free drug policy need not be confused with drug policy per se since they are not one and the same thing. Some time back news reports appeared in the local press revealing that first ever state level Essential Drugs List (EDL) has been customized and the same consists of a total of 1200 medicines. Such a huge list kills the basic aim and objective of formulating an Essential Drugs Lists since a concise list would have allowed concentration of all efforts vis-à-vis medicines management activities as well as limited resources on a small number of drugs leading to better results in terms of conservation of resources, large volume of purchases and consequently greater availability of essential medicines. Having 1200 drugs in EDL literally means including almost all drugs available in the market which would hardly translate into any tangible benefits for the patients. If the essential list finalized by JKMSC consists of 1200 drugs, it need correction as the essence of EDL lies in limiting the number of essential drugs based on individual facility/societal needs.

In conclusion appropriate measures need to be taken in the form of decisions, actions particularly for proper selection, quantification, forecasting, procurement, distribution and use of medicines to make the supply chain more efficient. Moreover disbursement of funds should also be sufficient and timely to cater to the needs of individual hospitals across all levels of care. Scattered and sparse budgetary allocations for medicines available with individual hospitals need to be pooled at the central level for optimal utilization of available resources resulting into more efficient procurement since centralized procurement and decentralized distribution has been found to improve access to medicines in all settings. All the activities related to medicines management and supply chain need to be carried out in accordance with standard guidelines and good practices involving only qualified and professional manpower. Evaluation of supply chain should be carried out regularly to monitor the performance. Facility specific policies and procedures with SOPs should be developed and adhered to for better compliance with existing standards. It is high time that the Govt. of J&K state starts implementing its premier drug policy that has been gathering dust over the past five years in the corridors of power, in letter and spirit. That shall go a long way in alleviating the sufferings and addressing the concerns of common masses regarding quality of medicines.

(Author teaches at the Dept. of Pharmaceutical Sciences, University of Kashmir and can be reached at ishaqgeer@gmail.com)

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